From AMS Glossary
(Abbreviated HFCs.) A collection of partially fluorinated hydrocarbons in use or under development as replacement compounds for the chlorofluorocarbons (CFCs).
The lack of chlorine in these compounds eliminates their potential to destroy stratospheric ozone. Also, the presence of H atoms makes them susceptible to removal from the atmosphere via reaction with hydroxyl radicals, reducing their effectiveness as greenhouse warming gases. The most widely used of this class of compounds is HFC-134a (CF3CFH2), which is currently being used in automobile air conditioners and domestic refrigeration applications.