High-performance liquid chromatography

From Glossary of Meteorology



high-performance liquid chromatography

(Abbreviated HPLC; also called high-pressure liquid chromatography.) Chromatographic technique similar to gas chromatography, except that various individual solvents, combinations of solvents, and changing concentrations of solvent are used in combination with stationary column phases to separate components of a liquid matrix.

Various detectors are used in HPLC, including UV (fixed and variable wavelength), refractive index, and conductivity detectors.


Copyright 2022 American Meteorological Society (AMS). For permission to reuse any portion of this work, please contact permissions@ametsoc.org. Any use of material in this work that is determined to be “fair use” under Section 107 of the U.S. Copyright Act (17 U.S. Code § 107) or that satisfies the conditions specified in Section 108 of the U.S.Copyright Act (17 USC § 108) does not require AMS’s permission. Republication, systematic reproduction, posting in electronic form, such as on a website or in a searchable database, or other uses of this material, except as exempted by the above statement, require written permission or a license from AMS. Additional details are provided in the AMS Copyright Policy statement.